A simple, accurate and cost efficient spectrophotometric method has been developed for the estimation of Clobazam in tablet dosage form. The optimum conditions for the analysis of the drug were established. The maximum wavelength (λ max) was found to be 230nm in 1N NaOH: Methanol (80:20). The percentage recovery of Clobazam was in the range of 99.50 -100.00%. Beers law was obeyed in the concentration range of 30-90μg/ml. Calibration curves shows a linear relationship between the absorbance and concentration. The line equation y=0.024144x-0.04595 with correlation coefficient of 0.99924 was obtained. Validation parameters were carried out as per the guidelines of International Conference for Harmonization. This method can be used in the industries for determination of Clobazam to analyze the quality of formulation without interference of the excipients.
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