New Bornscreening for Glucose-6-Phosphate Dehydrogenase Deficiency in Orissa, Ims & Sum Hospital: A Quantitative Assay

Objectives: To determine the incidenceof G6PD deficiencyin new born admittedto IMS &SUM HOSPITAL,Bhubaneswar. An objective
of the study was to estimate the incidence of G6PD deficiency among new-bornsand its association with different socio-demographic,
clinical and gestational characteristics.
Methods Atotal of 191new born blood samples were screened for the quantitative measurement of G6PD activity by enzymatic
colorimetric assay by a commercial kit Kinetic Method (G-SIX KIT). Any neonate with a value < 6.4 U/gHb was considered G6PD
deficient.
Results of the 191new-borns (120males, 71females) screened, 32 neonates were found to have G6PD deficiency (24 males, 8females).
The overall incidence of G6PD deficiency was 16.75%. Frequency in male population was 20% (24 out of 120 male neonates) and in
female population was 11.26% (8 out of 71 female neonates).