Extractive Visible Spectrophotometre Method development and validation for the estimation of Canagliflozin in pharmaceutical formulations

This work describes the development, validation and stable studies of a new, simple and reliable visible spectroscopy procedure for the analysis of Canagliflozin in pharmaceutical formulations. Studies were carried out to investigate the reaction between Canagliflozin with 5 different chromogenic dyes. All these dyes shown specific colors on reaction with Canagliflozin and prominent wavelength maxima was observed. All the developed methods were validated as per the ICH guidelines and results shows that the methods were valid. Formulation analysis shows good argument with the true values. Hence the proposed methods for the estimation of Canagliflozin are simple, rapid, accurate, economical and are useful for the estimation of Canagliflozin in pharmaceutical formulation.