Synthesis and Antimicrobial Activities of the 4-Chloro-N'-(4- Methoxybenzylidene)-Benzohydrazide Schiff Base Promoted by Metal(Ii) Ions

Metal complexes of novel Schiff base (HL) ligand, prepared via condensation of 4-chlorobenzohydrazide and 4-
methoxybenzaldehyde, are synthesized. The ligand is characterized based on elemental analysis, mass, IR and 1H NMR spectra. Metal complexes are reported and characterized based on elemental analyses, IR, 1H NMR, UV-visible spectroscopy,magnetic moment, molar conductance, ESR spectra and thermal analyses. From the elemental analyses, 1:2 [M]:[ligand]complexes are prepared with the general formulae [M(HL)2 Cl2; (M = Co(II), Ni(II) and Cu(II). The molar conductance datareveal that all the metal complexes are non-electrolytes. IR spectra show that HL is coordinated to the metal ions in a bidentatemanner with NO donor sites of the azomethine-N, and carboxylic-O atom. From the magnetic and UV-visible spectra, it isfound that the geometrical structures of these complexes are octahedral. The synthesized ligand, in comparison to its metal complexes is screened for its antibacterial activity against bacterial species. The activity data show that the metal complexes to be more potent/antimicrobial than the parent Schiff base ligand against one or more bacterial species.