Abstract

Diltiazem is in a group of drugs called calcium channel blockers belongs to a non-dihydropyridine (non-DHP class of compounds. Diltiazem is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders[1,2]. It works by relaxing the muscles of your heart and blood vessels. . By blocking the entry of calcium, Diltiazem decreases the force of contraction of the heart and its rate of contraction. It also relaxes the muscles surrounding the arteries, allowing the arteries to widen (dilate).

Issue

The Experiment 2013

Article Subject:

Biotechnology

KeyWords:

Diltiazem, HPLC, Linearity, validation.

Download PDF:

B.Lakshmi et al, The Experiment, January. 2013 Vol. .6(4), 365-371